T1 mapping in discrimination between hypertrophic and hypertensive cardiomyopathy
نویسندگان
چکیده
Background The differential diagnosis of hypertrophic phenotype remains challenging in clinical practice, in particular between hypertrophy cardiomyopathy (HCM) and increased left ventricular wall thickness (LVWT) due to systemic hypertension. Diffuse myocardial fibrosis is the characteristic feature in HCM, whereas hypertensive response is underpinned by addition of myofibrils in otherwise normal myocardial tissue. Late gadolinium enhancement (LGE) imaging provided important new way of differentiation between these two entities by separating those cases with evidence of regional fibrosis. Whereas approximately 60% of patients with HCM reveal visually discernable LGE, T1 mapping is highly discriminative, irrespective of the presence of LGE.
منابع مشابه
Exploiting Differences in Myocardial Compartments With Native T1 and Extracellular Volume Fraction for the Diagnosis of Hypertrophic Cardiomyopathy.
T1 Mapping in Discrimination of Hypertrophic Phenotypes: Hypertensive Heart Disease and Hypertrophic Cardiomyopathy: Findings From the International T1 Multicenter Cardiovascular Magnetic Resonance Study Rocio Hinojar, MD, MRes; Niharika Varma, MBBS, BSc; Nick Child, BM, MRCP; Benjamin Goodman, MSc; Andrew Jabbour, MD, PhD; Chung-Yao Yu; MBBS, MD; Rolf Gebker, MD, PhD; Adelina Doltra, MD, PhD; ...
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